AN ACE UP THEIR SLEEVE: A TRANSCRIPTOMIC APPROACH EXPOSES THE ACEI EFFLUX PROTEIN OF ACINETOBACTER BAUMANNII AND REVEALS THE DRUG EFFLUX POTENTIAL HIDDEN IN MANY MICROBIAL PATHOGENS

The era of antibiotics as a cure-all for bacterial infections appears to be coming to an end.The emergence of multidrug resistance in many hospital-associated pathogens has resulted in superbugs that are effectively untreatable.Multidrug efflux pumps are well known mediators of bacterial drug resistance.Genome sequencing efforts have highlighted an

This work investigates the fresh, mechanical and durability properties of normal, Self-Compacting Concrete (SCC) and Smart Dynamic Concrete (SDC), which are a new generation of concrete with a lower amount of cementitious content.SDC is a low-fine, self-compacting concrete, that combines the benefits of normal concrete (stability) and self-compacti

Glioblastoma (GBM) and other malignant gliomas are aggressive primary neoplasms of the brain that exhibit notable refractivity to standard treatment regimens.Recent large-scale molecular profiling has revealed distinct disease subclasses within malignant gliomas whose defining genomic features highlight dysregulated molecular networks as potential

Methamphetamine (MA) is an addictive psychostimulant, often abused by drug-addicted women during pregnancy.The offspring of drug-addicted mothers are often exposed to perinatal stressors.The present study examines Cleaners the effect of perinatal stressors and drug exposure on plasma oxytocin (OXY) levels in female progeny.Rat mothers were divided

Fungal endophytes play a pivotal role in tropical forest dynamics, influencing plant fitness through growth stimulation, disease suppression, stress tolerance, and nutrient mobilization.This study investigates the effects of region, leaf developmental stage, and tissue type click here on endophyte communities in tropical plants.Young and mature lea